Exosome Related Services
Exosomes are cell-derived vesicles that are present in many and perhaps all biological fluids, including blood, urine, and cultured medium of cell cultures. These are small vesicles (30-120 nm) containing nucleic acid and protein, perceived to be carriers of this cargo between diverse locations in the body. Exosomes are either released from the cell when multivesicular bodies fuse with the plasma membrane or they are released directly from the plasma membrane. It is becoming increasingly clear that exosomes have specialized functions and play a key role in, for example, coagulation, inter-cellular signaling, and waste management. Consequently, there is a growing interest in the clinical applications of exosomes. Exosomes can potentially be used for prognosis, therapy, and bio-markers for health and disease.
Luminous BioSciences offers isolation of Exosomes from culture media, serum, urine or saliva. Depending on your needs, we can isolate circulating RNA/DNA, exosomes, miRNA and exosomal proteins. We will perform a number of QC steps such as western blots, RT-PCR, etc. to ensure the quality of the isolated materials.
We offer following customized services:
Isolation of circulating RNA, DNA from serum, plasma, urine, saliva and cell culture media
Isolation of intact exosomes from serum, plasma, urine, saliva or cell culture media
Isolation of exosomal proteins
Isolation of exosomal miRNA
Isolation of exosomal DNA
To test the integrity and purity of the isolated materials we will perform a number of QC steps such as PCR or RT-PCR or western blot analysis using standard or custom probes/antibodies.
Likewise we can also isolate protein, RNA and genomic DNA from Bio-specimens (tissue). For your specific project needs, please call or send inquiries as follows:
Or call us:
North America: Tel: +1-301-296-8436 Toll Free +1-800-997-2610
Europe: Tel: +44-121-227-5283 Toll Free: 0800-015-4624